The Effectiveness of a Multimodal Brain Empowerment Program in Mild Cognitive Impairment: A Single-Blind, Quasi-Randomized Experimental Study

The present study aimed to determine a multimodal brain empowerment (MBE) program mitigate the modifiable risk factors in mild cognitive impairment (MCI), and its therapeutic effects are unknown. MBE encompassing (1) tDCS, light therapy, computerized therapy (TLC) (2) robot-assisted gait training, music core exercise (REM) interventions were randomly assigned 20 healthy young adults older with MCI. electroencephalography (EEG) power spectrum topographic event-related synchronization (ERS) analysis used assess intervention-related changes neural activity during program. Outcome: EEG results demonstrated that both TLC REM decreased delta waves increased theta, alpha, beta (p < 0.001). ERS showed activation frontal, temporal, parietal lobes REM. Such enhanced region of interest supports potential clinical benefits empowering function